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Figure 4.
Figure 4. Structure of CLC-ec1. This ribbon representation
of the homodimeric protein, viewed from the membrane plane
(extracellular side above, cytoplasmic side below), emphasizes
the anion-binding region. The inner and central chloride ions
are shown as green spheres, and the external glutamate (E148) is
indicated as a red sphere positioned at one of the carboxylate
oxygen atoms. An expanded representation of this region is shown
below, as viewed from the dimer interface, with the three
anion-binding sites indicated.
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