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Figure 4.
FIGURE 4. Representation of the interactions between enzyme
and substrate analogues. a, stick models for the interaction of
the enzyme with AMPPNP and MetSox. Carbon, oxygen, nitrogen,
phosphorus, and sulfur atoms are colored gray, red, blue,
salmon, and yellow, respectively. Three Mn^2+ are indicated in
pink spheres. Dotted lines designate hydrogen bonds and
coordination bonds to Mn^2+ ions. Residues without dotted lines
have hydrophobic interactions with the substrate. b, stick
models for the interaction of the enzyme with ADP and MetSox. c,
stick models for the interaction of the enzyme with ADP and
PPT-P.
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