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Figure 4.
Figure 4. Stereoview of the Changes in the mC5T Structure
The mutation of the guanine recognized by Arg177 to an
adenosine forces the side chain to reorient, displacing two
water molecules. The wild-type structure is semitransparent, and
illustrated in orange and teal for DNA and protein,
respectively; waters are red and hydrogen bonds are yellow. The
mutant structure is colored blue and purple for DNA and protein,
respectively. The waters in the mutant are colored green and the
hydrogen bonds are beige. The surface of the protein, excluding
the side chain for Arg177, from the mutant structure is rendered
in grey and is essentially identical to that of the wild-type
structure.
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