Figure 4.
Figure 4 Superimposed structures of inhibitors in the crystals.
Thr1-Lys4 of FR901451 (magenta sticks) bind to PPE in a similar
conformation to the linear inhibitor FR136706 (Kinoshita et al.,
2003[Kinoshita, T., Nakanishi, I., Sato, A. & Tada, T. (2003).
Bioorg. Med. Chem. Lett. 13, 21-24.]; displayed as blue sticks).
The above figure is reprinted
from an Open Access publication published by the IUCr:
Acta Crystallograph Sect F Struct Biol Cryst Commun
(2005,
61,
808-811)
copyright 2005.