Figure 4 - full size

 

Figure 4.
Fig. 4. Alignment of the PCNA structures in complex with the p21-derived peptide 139GRKRRQTSMTDFYHSKRRLIFS160 (green) with PCNA (cyan) (Protein Data Bank ID code 1AXC [PDB] ) and the PL peptide 1SAVLQKKITDYFHPKK16 (orange) with PCNA (blue). Key interacting residues are labeled. The phosphorylation site (S146) is highlighted, and the interaction with D149 (D10) is shown (purple).