Figure 4 - full size

 

Figure 4.
Figure 4. Stereo representations of the Den1-Nedd8 interface. A, Stereo representation of the interaction between the Nedd8 C-terminal tail (gray) and Den1 (yellow). Residues involved in interaction with Nedd8 are labeled and shown in bond representation. Amino acid residues thought to participate in hydrogen bonding interactions between these two molecules are denoted by red broken lines. B, Stereo representation focusing on the interactions between Nedd8 (gray) and Den1 (yellow) that do not involve the Den1 catalytic residues. Amino acid residues involved in the interaction are labeled and shown in bond representation with hydrogen bonding patterns depicted as red broken lines. C, Stereo representation focusing on the interactions between Nedd8 (gray) and Den1 (yellow) that do not involve the Den1 catalytic residues. Amino acid residues involved in the interaction are labeled and shown in bond representation with hydrogen bonding patterns depicted as red broken lines.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2005, 345, 141-151) copyright 2005.