Figure 5 - full size

Figure 5. Figure 5. Dimer Interface(A) Ribbon representation of the R348A mutant dimer, with ions bound in the ligand binding sites. Side chains of some residues on the interface are shown.(B) Stereoviews of the dimer interface from the wild-type (top) and mutant (bottom) domain structures. The αC of Gly221 is shown as a purple sphere. TM, transmembrane helix.

The above figure is reprinted by permission from Cell Press: Cell (2004, 119, 615-627) copyright 2004.