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Figure 4.
Figure 4: Comparison of template-independent and
template-dependent RNA polymerases. a, Ball-and-stick
representations of tRNA, AMPcPP, the catalytic carboxylates and
the ATP-interacting residues are shown on the Aa.LC head and
neck domains. The colouring scheme is the same as in Fig. 2,
except that the carbon atoms of Aa.LC are coloured orange. b,
Ball-and-stick representations of the primer RNA, the template
DNA, AMPcPP, the catalytic carboxylates and the ATP-interacting
residues are shown on the O helix in the T7 RNA polymerase
structure. In a and b, hydrogen bonds are shown as dotted lines.
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