Figure 4 - full size

 

Figure 4.
Figure 4. Examples of electron density maps revealing the position of hydrogen atoms. The 2F[o] -F[c] electron density map (gray) is contoured at +1.0 s, while the F[o] -F[c] difference electron density map (red) prior to inclusion of hydrogen atoms is contoured at +3.0 s and superimposed. A, Ile218; B, Lys203; C, Leu258; and D, Ile247.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2004, 338, 483-493) copyright 2004.