Figure 4.
Figure 4 Comparison of p47 UBA -ubiquitin, CUE -ubiquitin and
di-ubiquitin structures. (A) C[ ]traces
representing the superimposition of the 10 refined p47 UBA
-ubiquitin complex structures using the HADDOCK approach. p47
UBA is shown in gold and ubiquitin in green. (B) Ribbon
representation of the p47 UBA -ubiquitin complex. (C) Ribbon
representation of the structure of the yeast CUE2-1 domain
-ubiquitin complex in the same orientation as in (B). The CUE
domain is shown in purple (Kang et al, 2003; Shih et al, 2003).
(D) Ribbon representation of the structure of Lys48-linked
di-ubiquitin in the same orientation as in (B) (Cook et al,
1992, 1994; Cummings et al, 1995; Beal et al, 1998; Phillips et
al, 2001; Varadan et al, 2002).
The above figure is reprinted
from an Open Access publication published by Macmillan Publishers Ltd:
EMBO J
(2004,
23,
1463-1473)
copyright 2004.
]traces
representing the superimposition of the 10 refined p47 UBA
-ubiquitin complex structures using the HADDOCK approach. p47
UBA is shown in gold and ubiquitin in green. (B) Ribbon
representation of the p47 UBA -ubiquitin complex. (C) Ribbon
representation of the structure of the yeast CUE2-1 domain
-ubiquitin complex in the same orientation as in (B). The CUE
domain is shown in purple (Kang et al, 2003; Shih et al, 2003).
(D) Ribbon representation of the structure of Lys48-linked
di-ubiquitin in the same orientation as in (B) (Cook et al,
1992, 1994; Cummings et al, 1995; Beal et al, 1998; Phillips et
al, 2001; Varadan et al, 2002).