Figure 5 - full size

 

Figure 5.
Figure 5. Activation Loops Can Adopt a Wide Range of ConformationsThe superposition of the closed activation loop from FLT3 onto (A) the closed IRK-I activation loop (blue), (B) the partially open FGFR activation loop (red), and (C) the fully open IRK-A activation loop (blue).

The above figure is reprinted by permission from Cell Press: Mol Cell (2004, 13, 169-178) copyright 2004.