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Figure 4.
FIG. 4. Ligand binding sites of leukocyte receptor complex
immunoreceptors. A, the structure of KIR2DL2 (Protein Data Bank
entry 1efx [PDB]
) with residues contacting HLA-Cw3 displayed as ball-and-stick
models in gray (41). B, ILT2 (1g0x [PDB]
) with residues implicated in binding to UL18 (37, 51). C, Fc
 RI
(10W0) with residues contacting Fc displayed. D, the
structure of NKp46 with putative ligand binding residues
displayed. Residues in red correspond to the KIR binding site;
those in aqua and green correspond to the Fc RI and ILT2 binding
sites, respectively. The location of the potentially
glycosylated residue Thr104 is shown.
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