Figure 4 - full size

 

Figure 4.
Figure 4: Side-chain interactions between the subunits. a, A stereo view of the interactions between the three chains around the C lobe of TnC. b, The hydrophobic residues in the N lobe of TnC interacting with segment H3(I) of TnI. TnC, TnI and TnT are coloured pink, cyan and yellow, respectively. The amino acid residues involved in the interactions are shown in ball and stick representation. The three Ca^2+ ions bound to sites II, III and IV are shown by the black spheres.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (2003, 424, 35-41) copyright 2003.