Figure 4 - full size

 

Figure 4.
Fig. 4. Comparison of WT and S1S2J L650T/AMPA(AS) conformations. (A) Superposition of WT S1S2J/AMPA (gray) with S1S2J L650T/AMPA (AS form) protomer A (blue). (B) Superposition of WT S1S2J/AMPA (gray) with S1S2J L650T/AMPA(AS) protomer B (green). The black arrows in A and B indicate the axis of rotation relating the conformational difference between the WT and L650T structures. (C) Superimposed WT and mutant AMPA dimers.