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Figure 5.
Figure 5. Model of the Loading Process of the RuvA-RuvB
Complex on a Holliday JunctionEach of the three components in
this process was determined by X-ray analyses (forms I, II, and
III) or by an electron microscopic study (form IV). The RuvA
core region and domain III are colored by yellow and orange,
respectively. The RuvB subunit is depicted by a blue oval.
Red-trimmed ovals represent domain III bound to the RuvB
subunit. The RuvA-RuvB complex (form III) is regarded as the
preloading complex before forming the functional complex on a
Holliday junction (form IV). During the conversion from form III
to IV, the RuvB subunit that was previously connected with the
RuvA octameric core is no longer replaced by other partners.
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