Figure 4 - full size

 

Figure 4.
Figure 4. Interactions of RAE-1β-muNKG2D Complexes in the CrystalTwo views of the reciprocal, crystallographic interaction between muNKG2D homodimers are shown, a view perpendicular to a hypothetical cell-cell interface (top) and a view down onto the complexes (bottom). Molecules are shown as ribbon representations colored by domain (muNKG2D-A, blue; muNKG2D-B, purple; RAE-1β α1, yellow; and RAE-1β α2, orange). The approximate position of the crystallographic 6[1] screw axis is indicated, as are hypothetical cell surfaces and the paths of membrane anchor elements (black arrows). The position of Asn179 is indicated in red on the ribbons and by red arrows.

The above figure is reprinted by permission from Cell Press: Immunity (2002, 16, 77-86) copyright 2002.