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Figure 4.
Figure 4. Dimer−dimer interface. Upon the association of
two dimers, 3,400
Å^2 of the solvent-accessible surface is buried. There are
two views of the surface electrostatic potential of one dimer,
with the other dimer displayed as a ribbon. Basic regions on the
surface are blue, and acidic regions are red. The side chains of
the residues involved in dimer−dimer interactions are shown.
a, Front view of the highly hydrophobic surface involved in the
association with another dimer. b, Back view showing the highly
hydrophilic surface that is solvent exposed.
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