Figure 4 - full size

 

Figure 4.
Figure 4. Dimer−dimer interface. Upon the association of two dimers, 3,400 Å^2 of the solvent-accessible surface is buried. There are two views of the surface electrostatic potential of one dimer, with the other dimer displayed as a ribbon. Basic regions on the surface are blue, and acidic regions are red. The side chains of the residues involved in dimer−dimer interactions are shown. a, Front view of the highly hydrophobic surface involved in the association with another dimer. b, Back view showing the highly hydrophilic surface that is solvent exposed.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Biol (2002, 9, 117-120) copyright 2002.