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Figure 4.
Figure 4. Ribbon diagrams of the backbone of the Ca^2+ -CaM
solution structure, shown in red, and the 1 Å crystal structure
(1EXR) in blue. a, For the N-terminal domain, the
superposition is optimized for residues 29 -54 (helices II and
III), revealing the large difference in the orientation of helix
I (26°) and IV (22°). b, For the C-terminal domain, residues 102
-127 (helices VI and VII) are superimposed, showing much smaller
orientation differences of 15° and 10° for helix V and VIII,
respectively. c,d, Solution structures including side chains,
color coded according to their mobility as determined by 3J[CC]
and 3J[CN] couplings. Red indicates extensive rotameric  [1]
averaging; blue, single [1]
rotamers; and gray, residues with insufficient data for
accurately defining [1]
distributions. Eight Met residues (yellow) have unique [1]
angles but exhibit extensive [3]
averaging. Figures generated using MOLMOL49.
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