Figure 4 - full size

Figure 4. Fig. 4. (left). Architecture of integrin and G protein interfaces. The nucleotidebinding folds are in green, and the propellers are in gray. The integrin is shown in (A) and (B) and the G protein in (C) and (D). The helices at the core of each interface are indicated. Integrin's Arg261 and G protein's Lys210 project toward the respective propeller's central cavity. G (Ala^30-Leu348) and G (Ser2-Asn340) are shown. G protein coordinates were from (33).

The above figure is reprinted by permission from the AAAs: Science (2001, 294, 339-345) copyright 2001.