|
Figure 4.
Figure 4. Binding interface of CaM domains with the target
peptide. The N-terminal domains ((a), (c) and (e)) and
C-terminal domains ((b), (d) and (f)) of CaM are shown as a
surface model. (a) and (b) CaM-cCaMKKp comlex; (c) and (d)
CaM-smMLCKp complex; (e) and (f) CaM-CaMKIIp complex. The
surfaces were colored by the distance from the peptide. Red is
closer to the peptide while blue is far from the peptide. The
bound peptides are shown as a yellow tube. (Side-chains of
anchoring residues Leu337 and Phe352 ((a) and (b)), Leu813 and
Trp800 ((c) and (d)) Leu308 and Leu299 ((e) and (f)), are shown
as stick models. The Figure was produced using the program
MOLMOL.[39]
|