Figure 4 - full size

 

Figure 4.
Figure 4. Binding interface of CaM domains with the target peptide. The N-terminal domains ((a), (c) and (e)) and C-terminal domains ((b), (d) and (f)) of CaM are shown as a surface model. (a) and (b) CaM-cCaMKKp comlex; (c) and (d) CaM-smMLCKp complex; (e) and (f) CaM-CaMKIIp complex. The surfaces were colored by the distance from the peptide. Red is closer to the peptide while blue is far from the peptide. The bound peptides are shown as a yellow tube. (Side-chains of anchoring residues Leu337 and Phe352 ((a) and (b)), Leu813 and Trp800 ((c) and (d)) Leu308 and Leu299 ((e) and (f)), are shown as stick models. The Figure was produced using the program MOLMOL.[39]

The above figure is reprinted by permission from Elsevier: J Mol Biol (2001, 312, 59-68) copyright 2001.