Figure 5 - full size

 

Figure 5.
Figure 5. Surface analysis of the FcR structures. A surface analysis was performed using the program GRASP 39 with the crystal structures of FcgRIIa, FcgRIIb, FcgRIII and FceRIa as well as the modelled FcgRI. The colour coding spans from hydrophobic (green) to hydrophilic (red) with potential glycosylation sites indicated as blue balls. The viewpoint is indicated with respect to the front view, which shows an identical orientation as in Figure 2. The IgG binding site is surrounded by a black box in the FcgRIII molecule. The unique hydrophobic region on the N-terminal domain of FcgRIII is circled.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2001, 309, 737-749) copyright 2001.