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Figure 4.
Fig. 4. ELISA results demonstrating the relative inhibition of
binding of full-length soluble CR2 at 2 µg/ml to
plate-bound C3d by wild-type C3d (wt) compared to mutant C3d
(mut1, mut2, and mut4) at several concentrations. Wt and mut1
inhibited CR2-C3d binding similarly, whereas mut2 and mut4 have
lost most of their inhibitory capabilities and, thus, do not
effectively interact with CR2.
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