Figure 4.
Fig. 4. The dimerization interface in CD69. A, stereoview
of the dimerization interface in CD69. The two subunits of the
dimer are shown as ribbon diagrams in different colors, yellow
and green. The backbone of strand 0 and side
chains involved in hydrogen bonds or hydrophobic interactions
are represented by ball-and-stick models. Hydrogen bonds are
shown as white broken lines. B, cavity and static disorder at
the dimer interface. A close-up of the hydrophobic cluster at
the dimer interface is shown. The solvent-accessible surface and
the intersubunit cavity, as calculated with program SURFNET
(41), are shown as a semitransparent surface. For the right
subunit, the two alternate conformations for Tyr135 side chain
and the backbone atoms of surrounding residues are shown in
different colors, solid green and semitransparent green. In the
green subunit, strand 0 is shown
as a coil instead of an arrow for clarity.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2001,
276,
7312-7319)
copyright 2001.
0 and side
chains involved in hydrogen bonds or hydrophobic interactions
are represented by ball-and-stick models. Hydrogen bonds are
shown as white broken lines. B, cavity and static disorder at
the dimer interface. A close-up of the hydrophobic cluster at
the dimer interface is shown. The solvent-accessible surface and
the intersubunit cavity, as calculated with program SURFNET
(41), are shown as a semitransparent surface. For the right
subunit, the two alternate conformations for Tyr135 side chain
and the backbone atoms of surrounding residues are shown in
different colors, solid green and semitransparent green. In the
green subunit, strand