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Figure 4.
Figure 4. Hypothetically constructed superhelix structures
of three importin-bs. HEAT repeat helices from A3 to B9, stacked
side-by-side, are superposed. The residues of amino acid
residues 1-449 are used for the construction of the superhelix.
One pitch of superhelix is comprised of 24 molecules (impb449),
23 molecules (impb/IBB) and 23 molecules (impb/Ran),
respectively. Left, superhelix of impb449 (monomerI:uncomplexed
form); middle, superhelix of impb/IBB (PDB code 1QGK:RanGTP
uncomplexed form, but complexed with IBB in the C terminal half
of full length of importin-b); right, superhelix of impb/Ran
(PDB code 1IBR, chain B:RanGTP complexed form).
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