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Figure 4.
Figure 4. Comparisons of 9°N-7 and RB69 pols in
different (sub)domains to indicate loop segments that are
shorter in 9°N-7 pol. Least-squares C^a superposition was
performed over the region in blue, and the domains were
separated for side-by-side comparison. Loop regions are shown in
magenta and their residue endpoints are labeled. (a) Comparison
of the exonuclease domains. Indicated with purple asterisks are
the active site carboxylates (mutated to Ala in the case of the
9°N-7exo - pol used in this study). (b) Comparison of the
palm domains. The three active-site carboxylate groups are
depicted with side-chains.
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