Figure 4 - full size

 

Figure 4.
Figure 4. Stereoview of AMP-PNP. All major interactions with protein sidechains are indicated by dashed gray lines. The bound Mg2+ ions are indicated by black spheres. The phosphate atoms are shown in purple. Met109 can be seen behind the adenine base, blocking the hydrophobic pocket. Water molecules have been removed for clarity.

The above figure is reprinted by permission from Cell Press: Structure Fold Des (1999, 7, 1057-1065) copyright 1999.