Figure 4 - full size

 

Figure 4.
Figure 4. Structure of the Complex(A) Schematic representation of the structure of the complex, indicating the contacts of residues on Impβ with those of Ran. Interactions found in only one of the two molecules have an additional A,B identifier on the residue number. Open circles in Impβ[N] indicate the position of the B helices of the repeats with their numbers in red.(B) Ribbon representation of the complex with Ran in red, Impβ in green, superimposed with RanGDP in blue to highlight the potential clashes in switch I and the C-terminal end. GppNHp and Mg^2+ are shown as black ball-and-stick models.(C) Electrostatic surface potential of Impβ and RanGppNHp in and close to the interface (GRASP; [53]). The 180° rotation of Ran is indicated.

The above figure is reprinted by permission from Cell Press: Cell (1999, 97, 635-646) copyright 1999.