Figure 3 - full size

 

Figure 3.
Fig. 3. Interaction of the D^290ECH and the T322AT sequence of HCV RNA helicase. Note Asp290, Glu291, and His293 that form a part of the active site cavity are on a loop structure and point in the same direction. The backbones of the DECH motif and TAT sequence are in cyan and magenta, respectively, and the side chains are in green. The white dotted line indicates the hydrogen bond between His293 and Thr322.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (1998, 273, 15045-15052) copyright 1998.