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Figure 3.
Figure 3. Stereo Views in Ball-and-Stick Rendering of
Structural DetailsHydrogen bonds are shown as dotted lines;
oxygen atoms are colored red, nitrogens dark blue, and carbons
gray. This figure was generated using the programs MOLSCRIPT
([25]) and RASTER3D ( [29]).(A) The environment of Phe-135 of
Flt-1.(B) The region in Flt-1 corresponding to the “Y
corner” found in most Greek key barrel proteins.(C) A region
of the interface between VEGF (in dark gray) and Flt-1 (in light
gray) around the interaction between Asp-63 and Arg-224, showing
a chain of water molecules in the interface.
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