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Figure 3.
Figure 3. The epitopes recognized by A6 and gR38 (in red) and gR99 (in blue) on a ribbon representation of the
IFNg.IFNgR complex as determined by le Du et al. (unpublished results). IFNg (2
<
17 kDa) is shown in pink and
green, the IFNgR in white (N-terminal domain D1) and yellow (C-terminal domain D2) (see Figure 1). The red and
blue regions are those where changes are introduced in mutant 6 (CC loop) and 8 (EF loop) (red), and 13 (strand A),
14 (strand B) and 21 (C E loop) (blue) (see Table 1).
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