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Figure 3.
Figure 3. Major groove contacts of the QK50-TAATCC complex.
Three residues make base contacts in the major groove: Asn51
makes a pair of hydrogen bonds with the adenine at bp 3 (red);
lle47 makes hydrophobic contacts with the methyl group of the
thymine at bp 4 (purple); the primary conformation of Lys50
(yellow) makes hydrogen bonds with the O6 of the guanine at bp 5
and with the O6 and N7 atoms of the guanine at bp 6; the
secondary conformation of Lys50 (green) makes hydrogen bonds
with the O6 of the guanine at bp 5 and with the O4 of the
thymine at bp 4. Hydrogen bonds are shown as dashed lines and
van der Waals contacts are indicated with dotted spheres. For
clarity, water molecules have been omitted in this figure.
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