Figure 3 - full size

Figure 3. Fig. 3. hydrogen bondinteractions with inhibitorsare shown (top) with agraph showing te donor-acceptor dis- tances for the 21 nhibitor complexes (+ indicates an 0. . .H-N interaction, @ indicates an 0. . .H-N nteraction with an at theproton greater than 160'. and X indicates n 0. . .H-0 interaction). Some of theiteractions with the aspartate carbox- yls willbe van er Waals contactsratherthan hydrogen bonds (see text for discussion of proton locations).

The above figure is reprinted by permission from the Protein Society: Protein Sci (1994, 3, 2129-2143) copyright 1994.