Figure 3.
(a–e) Shown are the binding modes of DL06 (a), DL07 (b),
ZSTK474 (c), AS5 (d) and GDC-0941 (e) in the active site of
p110δ. Met752 is in its 'in' position for all these compounds.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Chem Biol
(2010,
6,
117-124)
copyright 2010.
