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Figure 3.
Residues involved in contacts are depicted as surface
representation. (a) Binding surface of VLRB.2D with contacting
residues from LRR1, LRRV and LRRVe in blue, from CP in red and
from LRRCT in orange. (b) Binding surface of VLR RBC36 (cyan) in
the complex with H-saccharide based on the structure PDB 3E6J^4.
(c,d) Comparison of VLR and antibody epitopes on HEL. Binding
surfaces of HEL in the VLRB.2D–HEL complex (c) and camel
cAb-Lys3–HEL based on the complex structure PDB 1MEL^14 (d).
Residues forming contacts in both complexes are green; residues
that interact exclusively with VLRB.2D or cAb-Ly3 are violet.
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