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Figure 3.
Figure 3. The Structural Basis of Histone Recognition by the
CBP Bromodomain
(A and B) Recognition of the acetyl-lysine
and its flanking residues in the H4-K20ac peptide by the human
CBP bromodomain, respectively.
(C and D) Recognition of the
acetyl-lysine and its flanking residues of the p53-K382ac
peptide by the human CBP bromodomain (PDB code: 1JSP),
respectively.
Side chains of protein or peptide residues
are color-coded by atom types in the same scheme as that in
Figure 2.
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