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Figure 3.
Figure 3. (a) Superposition of the architectures of
carbohydrate-recognition sites of human GRP-C and human
galectin-7. hGRP-C and hGal-7 are colored orange and blue,
respectively. hGRP-C residues E50, K52, V54, N63, R70, E73, and
S75 involved in sugar-binding and equivalent residues of hGal-7
are shown as stick models and their carbon atoms are colored
green and blue, respectively. Galactose carbon atoms are colored
gray. (b) Comparison of carbohydrate-binding pockets of hGal-7
and hGRP-C. In the left diagram, the groove labeled by a black
arrow is sugar-binding pocket of hGal-7. In the surface diagram
of hGRP-C, the region equivalent to hGal-7 binding pocket is
labeled by a black dashed pane.
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