Figure 3 - full size

Figure 3. Figure 3 Comparison of the structures of liganded wtTIM (1n55 ) and liganded ml1TIM (1ml1 ). (a) Schematic view. (b) Stereo picture. The wtTIM structure is coloured magenta and the ml1TIM structure is coloured gold. In wtTIM the carboxyl moiety of the ligand has a double conformation (up and down). The up conformation is the major conformation. In the structure of the ml1TIM-2PG complex only the down conformation is observed.

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2008, 64, 178-188) copyright 2008.