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Figure 3.
FIGURE 3. Stereoscopic views of the active site of the NCT
(A and C) and CTP (B and D) complexes. In panels A and B,
coordination bonds (red dashes) with Mn^2+ ions A and B (pink
spheres), and hydrogen bonds (red dashes) between the bound
nucleotide (magenta), key water molecules (red spheres), and the
protein are drawn. In panels C and D, Arg-182, the bound
nucleotide, Mn^2+ ions, and the terminal nucleotide of the
primer were removed prior to 20 rounds of refinement and (|F[o]|
- |F[c]|) electron density map calculation (3  contour). Figs. 2 and 3
were prepared using PyMOL (38).
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