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Figure 3.
Figure 3. Structure of AHIII TCR bound to p1049/A2. The AHIII
TCR α (green) and β (blue) chains, interact with the p1049/A2
surface via CDR loops. pMHC, consisting of a heavy chain, A2,
(yellow) and β[2]m (magenta), present the peptide, p1049 (red).
(Inset) The surface of the p1049/A2 is contacted by the CDR
loops of the AHIII TCR. Residues that have been mutated to
alanine for structural experiments (T163, W167, K66) are shown.
The Figure was generated using PDB coordinates 1LP9 and PyMol
[http://pymol.sourceforge.net/].
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