Figure 3 - full size

 

Figure 3.
Fig. 3. The stoichiometry of ORC1 binding at the ORB4 element. (A) Isothermal calorimetry data collected by using purified WH domain protein and a 40-mer DNA containing an ORB4 element. (B) Figure mapping the footprint data [(C)] onto the crystal structure. (C) Deoxyribonuclease I footprints across the ORB4 region. DNA sequences are indicated at the side for reference, with the ORB4 sequence boxed.

The above figure is reprinted by permission from the AAAs: Science (2007, 317, 1213-1216) copyright 2007.