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Figure 3.
Fig. 3. The structure of the ligand-binding core of GluR
 2
in complex with D-serine. (A) The D-serine-binding site of GluR
2–S1S2. The F[o] –
F[c] electron-density map of D-serine before introduction of
this molecule in the refinements is shown. D-serine and
potential hydrogen-bonding residues of GluR 2 are represented as
sticks, and dashed lines indicate hydrogen bonds. (B) Contour of
the ligand-binding cavity of GluR 2–S1S2 in complex
with D-serine (shown in gray). D-serine and GluR 2
residues within 3.5 Å are represented as sticks. No water
molecules were located within the hydrogen-bonding distance of
D-serine.
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