Figure 3 - full size

 

Figure 3.
(a) Structures of 1934.4, cl19 and 172.10 from TCR-pMHC complexes superimposed on I-A^u (colors as in Fig. 1). Red dashed lines, hydrogen bonds. (b) Interactions between TCR CDR1 and CDR2 loops and the I-A -helix. Highlighting indicates residues involved in interactions; black dashed lines, van der Waals forces; red dashed lines, hydrogen bonds. Top, interactions of 1934.4.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Immunol (2007, 8, 975-983) copyright 2007.