Figure 3.
Figure 3. Binding of the Purine Inhibitor (A and B)
Superimposition of PAK4 and PAK5 showing the (A) binding modes
of the purine inhibitor and (B) interaction with active site
residues in PAK4. A superimposition of the C-terminal lobes was
used to generate the figure shown in (A). PAK4 is shown in
yellow, and PAK5 is shown in orange.
The above figure is reprinted
from an Open Access publication published by Cell Press:
Structure
(2007,
15,
201-213)
copyright 2007.
