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Figure 3.
FIGURE 3. The ligand binding face of rat CD48. The surface
of the V-set domain of rCD48 is shown oriented to reveal the
ligand-binding GFCC'C'' face of the protein, as in Fig. 2. A,
the surfaces of residues whose mutation disrupts CD2 binding are
colored red and labeled, whereas those whose mutation has no
effect are colored green. B, the surface is uncolored to reveal
its flatness; the outline of the CD2 binding surface (as seen in
A) is shown. C, the surface is colored by its native
electrostatic potential calculated at neutral pH; blue
represents positive potential, white represents neutral, and red
represents negative potential contoured at ±8.5 kT.
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