Figure 3.
FIGURE 3. Nck1-SH2-Tir12 complex (shades of yellow)
superimposed on Nck2-SH2/Tir8 (green). A, the interactions of
SH2 domain and peptide are conserved superimposing the peptides.
B, the 17 nonconserved residues between Nck1- and Nck2-SH2
(green spheres) are distributed over the SH2 surfaces away from
the peptide-protein interface.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2006,
281,
18236-18245)
copyright 2006.
