Figure 3 - full size

 

Figure 3.
Figure 3. Comparison of CD8a interaction with YTS 105.18, H-2Kb and TL. (a) Expanded view of the interface between CD8a and YTS 105.18 Fab in stereo. The CD8aa/Fab complex is orientated as in Figure 1(a), with CD8a1 (maroon) on the left and YTS 105.18 Fab1 (blue) on the right. Hydrogen bonds are indicated by a broken line. (b) Equivalent stereo view of the interaction of CD8a1 (maroon) with class I pMHC (green), as defined in the CD8aa/H-2Kb complex structure.18 (c) Equivalent stereo view of the interaction between CD8a1 (maroon) and TL (purple), as defined in the CD8aa/TL complex structure.19

The above figure is reprinted by permission from Elsevier: J Mol Biol (2006, 358, 347-354) copyright 2006.