Figure 3.
Figure 3. Crystal Structures of Ligands 1 and 4 Bound in
Active and Inactive CDK2 (A–C) The overlay shown is
residues 77–143 of the same inhibitor (yellow, active; blue,
inactive) and with the substituted aniline derivative 4 (yellow)
bound in (B) monomeric CDK2 (green) and (C) active (pink) CDK2.
The above figure is reprinted
by permission from Cell Press:
Chem Biol
(2006,
13,
201-211)
copyright 2006.
