Figure 3 - full size

 

Figure 3.
Figure 3. Features of the Vts1p-SAM–RNA binding interface. (a) Schematic diagram of SRE recognition by Vts1p-SAM. Black dashed lines, hydrogen bonds; green dashed lines, hydrophobic interactions; blue background, the stem of the SRE; pink background, the pentaloop; red circles, phosphate groups; blue ovals, bridging water molecules. The labeled protein residues are colored according to their originating secondary structure elements as shown in the upper left schematic. (b) Stereo diagram of the Vts1p-SAM–SRE binding interface centered on SRE loop position G3. Red spheres, water molecules participating in bridging interactions between protein and RNA; dashed lines, hydrogen bonds involving the G3 base.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Mol Biol (2006, 13, 168-176) copyright 2006.