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Figure 3.
FIGURE 3. The binding interface of the
PIASX-P·SUMO-1 complex. A, stereo view of a ribbon
diagram of SUMO-1 (pink) in complex with the PIASX-P peptide
(light blue). The side chains of the key interface residues
(from which the intermolecular NOEs were observed) from SUMO-1
are shown in deep pink, and the side chains of residues of
PIASX-P involved in the interaction are shown in blue. B, a
similar view as that shown in A except that SUMO-1 is shown as a
surface representation with hydrophobic and aromatic residues
indicated in green. C, a similar view as in B with the surface
of SUMO-1 color-coded according to the electrostatic potentials.
Red to blue corresponds to negative to positive electrostatic
potentials. The side chains of residues 1-8 of the peptide are
shown with acidic side chains indicated in red, and basic side
chains indicated in blue. The side chains of all others residues
are indicated in green.
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