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Figure 3.
Fig. 3. Comparison of ligand-binding surfaces in sErbB1 and
sErbB4. (A) Conservation of sErbB1 TGF-  -binding residues in
sErbB4. Residues with atoms within4Åofa TGF- residue
are shown in red on surface representations of sErbB1 domains I
and III (4). Residues that are strictly conserved between the
ErbB1 ligand-binding site and ErbB4 are colored blue on surface
representations of sErbB4. (B) Electrostatic potential on the
ligand-binding surfaces of ErbB1 and ErbB4. Regions with
negative electrostatic potential are colored red and regions
with positive electrostatic potential are colored blue (scale
± 10 e/kT).
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